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21c Museum Hotel Louisville | Art Museum, Parking, Restaurant, Bar


21c Museum Hotel Louisville | Art Museum, Parking, Restaurant, Bar


Trip In Time Hotel Glance

21c Museum Hotel Louisville, the Art Museum Hotel Louisville, merges contemporary art with hospitality, featuring a curated art museum within its premises. This innovative concept offers guests a unique cultural experience. The hotel's modern accommodations, artistic ambiance, and on-site cultural exhibitions create an immersive and enriching stay. Located in downtown Louisville, it provides convenient access to the city's vibrant arts scene and attractions, making it a haven for art enthusiasts and curious travelers alike. Check out our details on the Louisville Museum Hotel below!

*Trip In Time cannot guarantee any information on this site is accurate. For up-to-date information, please contact the hotel. 


Our Review

Guests rave about the dining at Proof on Main.


Savor the essence of farm-fresh, local dining at Proof on Main, within 21c Museum Hotel Louisville. Delight in unique and colorful dishes that showcase the richness of the region, creating a memorable culinary experience in the heart of Louisville.


Discover an exquisite selection at the Proof on Main bar within 21c Museum Hotel Louisville, featuring 120+ Kentucky bourbons. Immerse yourself in the rich flavors and diverse profiles of these exceptional bourbons for an unparalleled tasting experience in the heart of Louisville.


Experience convenient parking at 21c Museum Hotel Louisville. Utilize the covered garage adjacent to the main entrance on 7th Street or opt for valet parking, offering in and out privileges for an additional cost. Enjoy a hassle-free stay in the heart of Louisville.


Enjoy a comprehensive fitness experience at the on-site fitness center of 21c Museum Hotel Louisville. Explore a range of equipment, including ellipticals, treadmills, bikes, a cable machine, and free weights. Elevate your well-being during your stay in Louisville.


Bring your furry companions to 21c Museum Hotel Louisville, where pets up to 50 pounds are welcomed. A pet cleaning fee of $40 ensures a pet-friendly stay, allowing you to enjoy the hotel's unique blend of art, hospitality, and comfort with your four-legged friend.


Located in the heart of downtown Louisville, 21c Museum Hotel immerses you in the city's vibrant cultural scene. Within walking distance of major attractions, including the Muhammad Ali Center and Louisville Slugger Museum, the hotel offers a perfect blend of art, luxury, and accessibility. Explore the lively energy of Main Street and the rich history of the surrounding area, ensuring an unforgettable stay in the heart of the Derby City.


Louisville Mega Cavern

Louisville Slugger Museum & Factory

Churchill Downs

Evan Williams Bourbon Experience

Indianapolis International Airport

Airport Shuttle

No shuttle service to the airport.


Start your day with a delicious breakfast at Proof on Main, available: 

Monday to Friday: 7 am to 10 am 

Saturday & Sunday: 8 am to 2 pm 

Indulge in American classics during these hours, setting the perfect tone for your day in the vibrant atmosphere of 21c Museum Hotel Louisville.


Relax and rejuvenate at the on-site spa of 21c Museum Hotel Louisville. Choose from a variety of massages, including Swedish, aromatherapy, reflexology, prenatal, sports, and deep tissue, ensuring a personalized and tranquil experience during your stay in Louisville.

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